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Clozapine
Antagonist of 5-HT 2A/2C receptor and several dopaminergic receptors, but showing only weak antagonism at the dopamine D2 receptor
Clozapine N-oxide
Metabolite of clozapine, activating human muscarinic designer receptors (DREADDs) and suppressing food intake.
CLP-290
Novel KCC2 modulator and prodrug of CLP-257, highly selective for KCC2 over related Cl- transporters
CM 346(Obenoxazine, Fabomotizole)
Novel anxiolytic and neuroprotective agent without any sedative or muscle relaxant actions
CM037
Novel selective aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor, binding within the aldehyde binding pocket of ALDH1A1 in a competitive mode of inhibition
CMF-019
The first potent biased small molecule agonist at the apelin receptor, increasing cardiac contractility in vivo
CMF-019 Potassium
The first potent biased small molecule agonist at the apelin receptor, increasing cardiac contractility in vivo