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FPMINT
A potent, irreversible and non-competitive inhibitor of equilibrative nucleoside transporters ENT1 and ENT2. FPMINT is more selective for ENT2 than ENT1
FPS-ZM1
A blood-brain-barrier permeant blocker of RAGE V domain-mediated ligand binding (Ki = 25, 148, & 230 nM, respectively, against Aβ40, HMGB1 & S100B, binding to sRAGE)
FR054
Novel inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect
FRAX486
An orally bioavailable and Blood-Brain Barrier (BBB) penetrable small molecule PAK (p21-activated kinase) inhibitor
FRAX597 HCl
Novel PAK inhibitor for the treatment of CNS disorders such as neuropsychiatric disorders or neurofibromatosis, and also for the treatment of cancer