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Triterpenoids

Triterpenoids

Reversible, voltage-dependent CFTR chloride channel blocker

Novel NMDA receptor glycine-site partial agonist, enhancing learning and memory

Broad spectrum MMP inhibitor

Non-peptidic selective SUMO-sentrin specific protease (SENP)1 protease inhibitor

a highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitor

Novel potent lactate dehydrogenase (LDHA) inhibitor

Novel potent and selective probe for the Bromodomains of CBP/EP300

Novel dual leucine zipper kinase (DLK, MAP3K12) inhibitor with activity in neurodegeneration models

A potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα, Kiapp is 21 nM for mTOR.

A potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitor

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