All Categories
Refine Search
KPT185
An orally bioavailable selective inhibitor of CRM1 amd displayes potent antiproliferative properties at submicromolar concentrations, induced apoptosis, cell-cycle arrest, and myeloid differentiation in AML cell lines and patient blasts.
KS15
Novel cryptochrome (CRY) inhibitor, enhancing E-box-mediated transcription by disrupting the feedback action of a circadian transcription-repressor complex.