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M2I-1
The first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the mitotic spindle assembly checkpoint (SAC)
M40403 (Imisopasem Manganese)
Nonpeptidyl superoxide dismutase mimetic, inhibiting dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects
M77976
Novel specific inhibitor of PDK4. binding to the ATP-binding pocket of PDK4 and causes local conformational changes with complete disordering of the ATP lid
M8-B
Selective and potent antagonist of the transient receptor potential melastatin-8 (TRPM8) channel
Macitentan
An orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).