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PT-Yellow (BDNCA3-D2)
Novel non-toxic fluorescent probe to label the renal proximal tubules in zebrafish
PT1
AMP-activated protein kinase (AMPK) activator. Stimulates AMPK heterotrimer (α1β1γ1) activity (EC50 = 0.3 μM). Thought to directly activate AMPK by antagonizing autoinhibition.
PTC124
Selectively induces ribosomal read-through of premature but not normal termination codons, with EC50 of 0.1 μM, may provide treatment for genetic disorders caused by nonsense mutations.