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R121919
Potent and orally active corticotropin-releasing factor receptor (CRFR1) antagonist, significantly preventing the onset of cognitive impairment in female mice and reducing cellular and synaptic deficits and beta amyloid and C-terminal fragment-beta..
R121919 (NBI-30775)
Potent and orally active corticotropin-releasing factor receptor (CRFR1) antagonist, significantly preventing the onset of cognitive impairment in female mice and reducing cellular and synaptic deficits and beta amyloid and C-terminal fragment-beta..
R121919 (NBI-30775) Hydrochloride
Potent and orally active corticotropin-releasing factor receptor (CRFR1) antagonist, significantly preventing the onset of cognitive impairment in female mice and reducing cellular and synaptic deficits and beta amyloid and C-terminal fragment-beta..
R306465 ( JNJ-16241199,)
A novel hydroxamate-based histone deacetylase (HDAC) inhibitor with broad-spectrum antitumour activity against solid and haematological malignancies in preclinical models
R55
Novel enhancer of the levels of retromer proteins, shifting APP away from the endosome, decreacing the pathogenic processing of APP