All Categories

TG53

Novel inhibitor of tissue transglutaminase (TG2) and fibronectin (FN) protein-protein interaction

TG6-129

Novel EP2 Selective Antagonist

TGF-B-recpotor Inhibitor

TGFß Inhibitor A-83-01

Selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptorALK7 ; transforming growth factor (TGF)-β inhibitor 

TGX-221

A Potent and specific PI3K inhibitor

TH 5487

Novel selective active-site inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)

TH287

First-in-class nudix hydrolase family inhibitor, potently and selectively engaging and inhibiting the MTH1 protein in cells

TH588

First-in-class nudix hydrolase family inhibitor, potently and selectively engaging and inhibiting the MTH1 protein in cells

THAL-SNS-032

Novel selective CDK9 degrader consisting of a CDK-binding SNS-032 ligand linked to a thalidomide

Thalidomide

Immunosuppressive and anti-angiogenic agent, inhibiting release of TNFalpha from monocytes, and modulating other cytokine action.

Thalifoline

Alkaloids

THCCC

Novel Dual Metabotropic Glutamate Receptor 2/3 Negative/Positive Allosteric Modulator, PHCCC (GLXC-02563) analog