TED-347
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Novel covalent inhibitor of TEAD4-Yap1 protein-protein interaction in mammalian cells, blocking iTEAD transcriptional activity and inhibiting glioblastoma cell viability
| Technical Data | |
| Chemical Formula | C15H11ClF3NO |
| Molecular Weight | 313.7 |
| Solubility | DMSO |
| IUPAC/Chemical Name | InChI=1S/C15H11ClF3NO/c16-9-14(21)12-6-1-2-7-13(12)20-11-5-3-4-10(8-11)15(17,18)19/h1-8,20H,9H2 |
| Purity | 98% by HPLC |
| Storage | 0°C (short term), -20°C (long term), desiccated |
| InChI Key | JPVDFGYNLUBCSD-UHFFFAOYSA-N |
| InChl Code | TED 347 |
| Smiles | O=C(C1=CC=CC=C1NC2=CC=CC(C(F)(F)F)=C2)CCl |
| References | TED-347 |
| Synonym | TED347 |

