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CRIPGBM

CRIPGBM
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Unit Price Qty
5 mg $215.60
10 mg $343.00

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Novel potent apoptosis inducer in Glioblastoma multiforme (GBM; grade IV astrocytoma) cancer stem cells (CSCs), inducing caspase 1-dependent apoptosis by binding to receptor-interacting protein kinase 2 (RIPK2) and acting as a molecular switch, which reduces the formation of a prosurvival RIPK2/TAK1 complex and increases the formation of a proapoptotic RIPK2/caspase 1 complex







Technical Data
Chemical Formula C26H20FClN2O2
Molecular Weight 446.91
Solubility DMSO
Purity 98% by HPLC
Storage 0°C (short term), -20°C (long term), desiccated