Fluorofenidone
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Novel antifibrotic and anti-inflammatory agent, restoring caveolin 1 expression and inhibiting mitogen-activated protein kinase signaling pathway, also inhibiting phosphorylation of extracellular signal-regulated kinase, P38, and c-Jun N-terminal kinase
| Technical Data | |
| Chemical Formula | C12H10FNO |
| CAS Number | 848353-85-5 |
| Molecular Weight | 203.22 |
| Solubility | DMSO |
| IUPAC/Chemical Name | 12 |
| Purity | 98% by HPLC |
| Storage | 0°C (short term), -20°C (long term), desiccated |
| InChI Key | JDZYVVUJIQYGRX-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C12H10FNO/c1-9-5-6-12(15)14(8-9)11-4-2-3-10(13)7-11/h2-8H,1H3 |
| Smiles | O=C1C=CC(C)=CN1C2=CC=CC(F)=C2 |
| References | 1) Tang J, et Spermidine-mediated poly(lactic-co-glycolic acid) nanoparticles containing fluorofenidone for the treatment of idiopathic pulmonary fibrosis. Int J Nanomedicine. 2017 Sep 8 |
| Synonym | Fluorofenidone |

