G140
-
Total: $0.00
$0.00
| Unit | Price | Qty |
|---|---|---|
| 5 mg | $259.60 |
|
| 10 mg | $413.00 |
|
Select A Tab:
Novel potent cGAS-specific inhibitor for repression of dsDNA-triggered interferon expression ( IC50 of 14 nM and 442 nM for h-cGAS and m-cGAS, respectively)
| Technical Data | |
| Chemical Formula | C17H16Cl2N4O2 |
| Molecular Weight | 379.24 |
| Solubility | DMSO |
| IUPAC/Chemical Name | 74(11) |
| Purity | 98% by HPLC |
| Storage | 0°C (short term), -20°C (long term), desiccated |
| InChI Key | NVPFAXHXXODQRO-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C17H16Cl2N4O2/c1-22-4-2-13(21-22)9-6-11(18)16(19)17-15(9)10-7-23(14(25)8-24)5-3-12(10)20-17/h2,4,6,20,24H,3,5,7-8H2,1H3 |
| Smiles | O=C(N(C1)CCC(N2)=C1C3=C2C(Cl)=C(Cl)C=C3C4=NN(C)C=C4)CO |
| References | 1) Rhee SY, et al. A systematic review of the genetic mechanisms of dolutegravir resistance. J Antimicrob Chemother. 2019 Nov 1 |