GS-441524
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| Unit | Price | Qty |
|---|---|---|
| 5 mg | $162.80 |
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| 10 mg | $259.00 |
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A novel precursor of potent inhibitor of feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. It only becomes effective pharmacologically when it was formed as its triphosphate analog in situ.
GS-441524 is originally identified as an active metabolite of Remdesivir that is an antiviral drug, a novel nucleotide analog prodrug.
REFERENCE:
1) Murphy BG, etc. The nucleoside analog GS-441524 strongly inhibits feline infectious peritonitis (FIP) virus in tissue culture and experimental cat infection studies. Vet Microbiol. 219:226-233 (2018). doi: 10.1016/j.vetmic.2018.04.026. Epub 2018 Apr 22. PubMed PMID: 29778200
2) J Feline Med Surg. 2019 Apr; 21(4): 271–281.
| Technical Data | |
| Chemical Formula | C12H13N5O4 |
| CAS Number | 1191237-69-0 |
| Molecular Weight | 449.51 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Storage | 0°C (short term), -20°C (long term), desiccated |
| InChI Key | BRDWIEOJOWJCLU-LTGWCKQJSA-N |