JNJ-64619178
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| Unit | Price | Qty |
|---|---|---|
| 5 mg | $198.00 |
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| 10 mg | $315.00 |
|
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Novel potent and selective PRMT5 inhibitor, demonstrating tumor regression in a biomarker-driven human small cell lung cancer
| Technical Data | |
| Chemical Formula | C22H23BrN6O2 |
| CAS Number | 2086772-26-9 |
| Molecular Weight | 483.37 |
| Solubility | DMSO |
| IUPAC/Chemical Name | (1S,2R,3S,5R)-3-(2-(2-Amino-3-bromoquinolin-7-yl)ethyl)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclopentane-1,2-diol |
| Purity | 98% by HPLC |
| Storage | 0°C (short term), -20°C (long term), desiccated |
| InChI Key | DBSMLQTUDJVICQ-CJODITQLSA-N |
| InChl Code | InChI=1S/C22H23BrN6O2/c23-15-8-12-3-1-11(7-16(12)28-21(15)25)2-4-13-9-17(19(31)18(13)30)29-6-5-14-20(24)26-10-27-22(14)29/h1,3,5-8,10,13,17-19,30-31H,2,4,9H2,(H2,25,28)(H2,24,26,27)/t13-,17+,18+,19-/m0/s1 |
| Smiles | BrC1=C(N)N=C(C=C(CC[C@@H]2[C@@H](O)[C@@H](O)[C@H](N3C(N=CN=C4N)=C4C=C3)C2)C=C5)C5=C1 |
| References | 1) Tongfei Wu, et al. Abstract 4859 |