LDE-225
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A Smoothened (Smo) antagonist, inhibiting Hedgehog (Hh) signaling with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
| Technical Data | |
| Chemical Formula | C26H26F3N3O3 |
| CAS Number | 956697-53-3 |
| Molecular Weight | 485.5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Storage | 0°C (short term), -20°C (long term), desiccated |

