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LGH447

LGH447
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5 mg $217.80
10 mg $346.50

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Potent and specific pan-PIM inhibitor, inhibiting proliferation of several AML cell lines, showing dual antitumoral and bone antiresorptive effects


































































Technical Data
Chemical Formula C24H23F3N4O
CAS Number 1210608-43-7
Molecular Weight 440.47
Solubility DMSO
IUPAC/Chemical Name PIM447
Purity 98% by HPLC
Storage 0°C (short term), -20°C (long term), desiccated
InChI Key VRQXRVAKPDCRCI-ZNMIVQPWSA-N
InChl Code LGH 447
Smiles O=C(NC1=C([C@H]2C[C@@H](N)C[C@@H](C)C2)C=CN=C1)C3=NC(C4=C(F)C=CC=C4F)=C(F)C=C3
References LGH447
Synonym LGH-447