ML246 (Metarrestin)
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Novel inhibitor of the perinucleolar compartment (PNC)
| Technical Data | |
| Chemical Formula | C31H30N4O |
| CAS Number | 1443414-10-5 |
| Molecular Weight | 474.6 |
| Solubility | DMSO |
| IUPAC/Chemical Name | LSL-KrasG12D/+ |
| Purity | 98% by HPLC |
| Storage | 0°C (short term), -20°C (long term), desiccated |
| Smiles | O[C@H]1CC[C@H](N(C=NC2=C3C(C4=CC=CC=C4)=C(C5=CC=CC=C5) N2CC6=CC=CC=C6)C3=N)CC1 |
| References | 1) Vilimas T, et al. Pharmacokinetic evaluation of the PNC disassembler metarrestin in wild-type and Pdx1-Cre |

