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LDN-57444
Creates dramatic alterations in synaptic structure and function, increasing spine size while decreasing spine density in hippocampal neurons.
LDN193189 HCl
A selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.
LED209
Nvel non-toxic inhibitor of the binding signals to QseC, preventing its autophosphorylation and consequently inhibiting QseC-mediated activation of virulence gene expression.
Lenalidomide
Thalidomide analog known to display TNF-α secretion inhibition and possesses immunomodulatory properties