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NSC-658497

Novel inhibitor of SOS1-Ras interaction, dose-dependently inhibiting SOS1 GEF activity

NSC-668036

Wnt signaling inhibitor, binding the PDZ domain of the Dishevelled (Dvl) protein

NSC-87877

Potent inhibitor of SHP2 and SHP1 protein tyrosine phosphatases

NSC109555 Dimesylate

Selective, reversible, ATP-competitive Chk2 inhibitor

NSC117079

Novel pan-PHLPP inhibitors (selective for PHLPP1 and PHLPP2)

NSC15765 (DNA2-IN-C5)

Novel specific inhibitor of DNA2 nuclease activity

NSC319726

Reactivator of mutant p53.

NSC47924

Novel 37/67kDa laminin receptor (LR) inhibitor, affecting both the direct 37/67kDa LR-PrP(C) interaction in vitro and the formation of the immunocomplex in live cells, inducing a progressive internalization of 37/67kDa LR and stabilization of PrP(C..

NSC49652

Inhibitor of DNA double strand break (DCB) repair

NSC5844

Agonist of C-C chemokine receptor type 1 (CCR1)

NSC635437

Inhibitor of EWS-FLI1 oncoprotein in Ewing's Sarcoma

NSC666715

Novel Inhibitor of Strand-Displacement Activity of DNA Polymerase