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Novel potent inhibitor of integrin-linked kinase (ILK), suppressing cancer cell proliferation in vitro and in vivo

Novel potent inhibitor of integrin-linked kinase (ILK), suppressing cancer cell proliferation in vitro and in vivo

Potent and highly selective CB1 antagonist

Peripherally selective cannabinoid receptor 1 antagonist

Alkaloids

Alkaloids

Novel potent TOPK (T-lymphokine-activated killer cell-originated protein kinase) inhibitor

Orally administrative selective inhibitor of maternal embryonic leucine zipper kinase (MELK) selective inhibitor

An orally bioavailable, small molecule inhibitor of BRD2, BRD3, and BRD4 (EC50s = 10 9 nM)

Novel potent and selective ARTD10 inhibitor, rescuing HeLa cells from ARTD10-induced cell death and sensitizing cells to DNA damage

ATP-competitive, selective dual inhibitor of mTORC1/mTORC2

Alkaloids

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