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Oprozomib (ONX-0912, PR-047)
An ORALLY ACTIVE and irreversible inhibitor of 20S proteasome inhibitor targeting primarily chymotrypsin-like activity
Orantinib (TSU-68 Or SU6668)
An ATP-competitive, orally bioavailable receptor tyrosine kinase (RTK) inhibitor targeting PDGFR, VEGF and FGFR