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Olmesartan Medoxomil
A prodrug that is metabolized in vivo to RNH-6270; a nonpeptide angiotensin II antagonist that potently inhibits angiotensin binding to the AT1 receptor (IC50 = 7.7 nM) without affecting binding to the AT2 receptor
Oltipraz Metabolite M2
Metabolite of the chemopreventive agent oltipraz, inhibiting lipogenesis and enhancing mitochondrial function, including fuel oxidation
Omecamtiv Mecarbil(CK1827452)
A selective sarcomere-directed cardiac myosin activator with an EC50 of 0.6 μM.