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A potent inhibitor of CDK4, with an IC50 of 3.8 nM, with little inhibitory activity against CDKs 1,2,5 and 8.
Competitive serotonin 5-HT3 receptor antagonist
Sesquiterpenoids
Triterpenoids
Orally available EP1 receptor antagonist.
Flavonoids
A selective inhibitor of the β5i (LMP7) subunit of the immunoproteasome and demonstrates significantly weaker activity at the β5 subunit of the constitutive proteasome
Steroids
