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A selective inhibitor of B-RAF protein kinase carrying V600E mutation

Novel tyrosine kinase (TK) inhibitor, selectively targeting c-Kit and c-Fms

Potent inhibitor of the nuclear DNA polymerases, resulting in inhibition of DNA synthesis and/or DNA repair

Highly potent and selective inhibitor of glutamate carboxypeptidase 2 (GCP II/N-acetylated a-linked dipeptidase/NAALADase)

Novel FAK inhibitor, selectively promoting tumor cell apoptosis in three-dimensional environments

Congeneric α7 nAChR agonist

Novel inhibitor of the interaction between ß-catenin and T cell factor 4 (Tcf4), disrupting the Wnt signaling pathway

ATP site competetive inhibitor of CDK2 and CDK5

Flavonoids

Lignans

Potent and selective antagonist of the chemokine receptor CXCR4

Phenylpropanoids

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