Cabozantinib (XL184, BMS-907351)
Select A Tab:
A pan tyrosine kinase inhibitor that primarily targets VEGFR2 (IC50 = 0.035 nM) and c-Met (IC50 = 1.3 nM) but also inhibits RET, c-Kit, Axl, FLT3, and Tie2 (IC50s = 5.2, 4.6, 7, 11.3, and 14.3 nM, respectively).
| Technical Data | |
| Chemical Formula | C28H24FN3O5 |
| CAS Number | 849217-68-1 |
| Molecular Weight | 501.5 |
| Purity | >=98% |
| Storage | 0°C (short term) -20°C (long term) desiccated |

