J014
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Novel cGAS-specific inhibitor for repression of dsDNA-triggered interferon expression ( IC50 of 100 nM and 60.0 nM for h-cGAS and m-cGAS, respectively)
| Technical Data | |
| Chemical Formula | C15H11N5O3 |
| Molecular Weight | 309.29 |
| Solubility | DMSO |
| IUPAC/Chemical Name | 4-Nitro-N-(4-phenylpyridin-2-yl)-1H-pyrazole-5-carboxamide |
| Purity | 98% by HPLC |
| Storage | 0°C (short term), -20°C (long term), desiccated |
| References | Lodoe Lama, et al Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression, Nature Communications 10 |

