SIS3 HCl
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Novel specific inhibitor of TGF-ß1/ALK-5 phosphorylation of Smad3
| Technical Data | |
| Chemical Formula | C28H28ClN3O3 |
| CAS Number | 521984-48-5 |
| Molecular Weight | 489.99 |
| Solubility | 49 mg/mL in DMSO |
| IUPAC/Chemical Name | /h4-12,14,16-17H,13,15,18H2,1-3H3 |
| Purity | 98% by HPLC |
| Storage | 0°C (short term), -20°C (long term), desiccated |
| InChI Key | CDKIEBFIMCSCBB-CALJPSDSSA-N |
| InChl Code | InChI=1S/C28H27N3O3.ClH/c1-30-27(19-8-5-4-6-9-19)22(23-10-7-14-29-28(23)30)11-12-26(32)31-15-13-20-16-24(33-2)25(34-3)17-21(20)18-31 |
| Smiles | O=C(N4CCC(C=C(OC)C(OC)=C5)=C5C4)/C=C/C2=C(C3=CC=CC=C3)N(C)C1=NC=CC=C12.Cl |

