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Diterpenoids

Class IB antiarrhythmic; sodium channel blocker

Dopamine antagonist, blocking presynaptic but stimulating postsynaptic alpha-adrenoceptors

A rationally designed, oral, isotype-selective, small molecule HDAC inhibitor

Inhibitor of autophagy

An inhibitor of the menin-MLL interaction (IC50 = 31 nM; Kd = 23.6 nM)

Potent inhibitor of the menin-MLL interaction

Potent irreversible MALT1 inhibitor, suppressing NF-κB signaling and ABC-DLBCL in vivo

Novel potent Menin-MLL inhibitor

T-type Ca2+ channel blocker and positive modulator of TRPM7; Antihypertensive.

Sesquiterpenoids

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