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A novel ATP-competitive multitargeted inhibitor of activated c-Met kinases

An isonicotinamide small molecule, acting as a potent and selective Orexin receptor antagonist

A dual orexin receptor antagonist that blocks both OX1R and OX2R

A dual orexin receptor antagonist that blocks both OX1R and OX2R

An inhibitor of PARP 1 and 2

An inhibitor of PARP 1 and 2

A potent, selective and ATP competitive inhibitor of Aurora A

Novel Systemic pan-AMPK activator, improving glucose homeostasis but inducing cardiac hypertrophy

A moderately potent γ-secretase inhibitor, which reduces Aβ40 production

A potent, selective and orally active Orexin OX2 Receptor Antagonist for potential treatment of insomnia

A potent SMO Inhibitor of the Hedgehog Pathway, highly active against Medulloblastoma and Basal Cell Carcinoma.

Agonist of the transient receptor potential channel ML3 (TRPML3)

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