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Coumarins
A potent, orally bioavailable and ATP-competitive inhibitor of p21-activated kinase (PAK)
A potent, selective, orally bioavailable c-Met kinase inhibitor
Novel potent, orally bioavailable inhibitor of cholesteryl ester transfer protein (CETP)
In II phase clinical trials for the treatment of post-traumatic stress disorder.
A potent, selective and orally active ATP-competitive PI3K and mTOR inhibitor
Novel potent and selective human Nav1.7 blocker
Novel selective TRPM8 antagonist
Potent and selective dual inhibitor of PI 3-kinase/mTOR
Novel potent and selective glucagon receptor antagonist
Novel selective inhibitor of sodium-phosphate cotransporter 2a (NaPi2a or SLC34A1)
