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Selective myeloperoxidase (MPO) inhibitor
A highly selective and potent PDE10A inhibitor with an IC50 of 0.37 nM
Novel subtilisin kexin isozyme-1/site-1 (SKI-1/S1P) protease inhibitor
Dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor
Novel HIV-1 maturation inhibitor
The first highly specific inhibitor of p70 ribosomal S6 kinase (S6K1)
Novel potent and selective PI3K inhibitor
Novel, potent and specific inhibitor of sphingosine kinase-1
A potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 catalytic activity
Novel focal adhesion kinase (FAK) inhibitor
pan-CK1delta/epsilon inhibitor
Novel AMPK agonist, activating AMPK in hepatocytes and skeletal muscle