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PF-794

Novel potent, ATP-competitive TNIK inhibitor, also inhibiting MINK1 and MAP4K

PF-8380

Potent autotaxin inhibitor, serving as a tool compound for elucidating LPA's role in inflammation.

PF-9184

Highly potent and selective inhibitor of recombinant human microsomal prostaglandin synthase 1 (mPGES-1)

PF-9366

Novel inhibitor of human methionine adenosyltransferase 2A (Mat2A), the extrahepatic isoform

PF-CBP1

Selective CREB Binding Protein Bromodomain Inhibitor. modulating key inflammatory genes in primary macrophages and downregulating RGS4 in neurons linked to Parkinson's disease

PF0477736

A selective, potent ATP-competitive Chk1 inhibitor

PF06447475

Highly potent, selective, brain penetrant, and in vivo active LRRK2 kinase inhibitor.

PF3845

Selective fatty acid amide hydrolase (FAAH) inhibitor

PF4618433

PF-4618433 shows improved PYK2 potency, reduced p38 activity

PF573228

Potent and selective inhibitor of focal adhesion kinase (FAK)

PF74

Selective HIV-1 inhibitor triggering premature HIV-1 uncoating in target cells and mimicking the activity of the retrovirus restriction factor TRIM5

PF9601N

Potent and selective MAO-B inhibitor in treatment of Parkinson's disease