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Topiroxostat
elective xanthine oxidoreductase inhibitor for the treatment of gout and hyperuricemia, causing transitional cell tumors and effectively reducing the serum urate level
Topotecan
The hydrochloride salt of a semisynthetic derivative of camptothecin with antineoplastic activity
Torin2
Potent and selective mTOR inhibitor (IC50 = 2.1 nM). Displays 800-fold cellular selectivity for mTOR over PI3K (cellular EC50 values are 0.25 and 200 nM for mTOR and PI3K respectively). Orally available.