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TP-3654
The second-generation PIM inhibitor, displaying submicromolar activity in pharmacodynamic biomarker modulation, cell proliferation studies, and colony formation assays
TP-434
Novel potent broad-spectrum antibiotic, actively against multidrug-resistant bacteria, including those expressing extended-spectrum ß-lactamases and mechanisms conferring resistance to other classes of antibiotics, including carbapenem resistance
TRAM 34
Potent inhibitor of the intermediate-conductance Ca2+-activated K+ channel, blocking Kv1.3, Kv1.4, Kv7.2+Kv7.3 and Nav1.4