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Trans-ISRIB
Potent Inhibitor of PERK Signaling, displaying significant enhancement in spatial and fear-associated learning
Trans-pDMA
Effective constitutive androstane receptor (CAR) activator; Inhibitor of the gluconeogenic genes PEPCK and G6Pase through suppression of HNF4a and FOXO1 transcriptional activity
Trans-Zeatin
A member of the plant hormone family known as ‘cytokinins’, which regulate cell division, development, and nutrient processing.
TRC-794
Novel small molecule activator of PP2A (SMAP), negatively regulating c-myc in small cell lung cancer
Trelagliptin
A long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D).