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JAY2-22-33
Novel neuroprotective agent, significantly reducing Aβ toxicity by delaying paralysis and improving cognitive performances in a transgenic mouse model of AD
JCP174-Et
Suicide substrate for serine proteases, irreversibly inactivating human leukocyte (HL) elastase, porcine pancreatic (PP) elastase, and chymotrypsin
JH-RE-06
A novel inhibitor of mutagenic translesion synthesis (TLS), disrupting mutagenic TLS by preventing recruitment of mutagenic POL ζ, targets a nearly featureless surface of REV1 that interacts with the REV7 subunit of POL ζ, inducing REV1 dimerizatio..